Main Faction Quests
- When Freedom Calls: Kill the Raiders in the Museum of Freedom.
- Sanctuary: Learn the art of crafting.
- Taking Independence: Seize a castle and expand your influence.
- Old Guns: Decorate with weapons.
- Inside Job: Build a teleporter.
- Form Ranks: Recruit more Minutemen.
- Defend the Castle: An Institute assault forces your hand.
- The Nuclear Option (The Minutemen): Sneak into and defeat The Institute.
- With Our Powers Combined: Use your settlements against The Brotherhood of Steel.
Radiant Quests: Recruitment
- The First Step: Clear out the Corvega Assembly Plant.
- Raider Troubles at Oberland Station: Kill the Raiders in Back Street Apparel.
- Kidnapping: Rescue a settler or get out your wallet.
- Greenskins: Kill Mutants for Mutants.
- Clearing the Way: Kill 'em all to make room for a new settlement.
- Taking Point: Starlight Drive-In: Create a radio beacon.
- Ghoul Problem: I ain't afraid of no Ghoul.
- Rogue Courser: Find and kill a Courser.
- Resettle Refugees: Solve a humanitarian crisis.
Radiant Quests: Ownership
- Defend a Settlement: Build turrets to defend settlers.
- Defend Artillery at a Settlement: Defend a settlement's artillery.
- Stop the Raiding: Kill some Raiders to help your fellow settlers.
- Kidnapped Trader: To pay or not to pay a hostage's ransom.
- Water, Food or Power: Your workshop talents are always needed, always appreciated.
- Suspected Synth: Find an artificial man among men.